Roche friabilator

  • A Roche friabiliator is an instrument consists of a plastic chamber for placing the tablets which is attached to a horizontal axis. The drum has an inside diameter of 287mm and is about 38mm in depth, made of a transparent synthetic polymer with polished internal surface. A set of pre weighed tablets [if one tablet weigh 650mg or less then approx 6.5 g of total weight should be taken and for more than 650mg/tablet weight, 10 tablets should be taken] (3) are placed in the plastic chamber revolving at 24-25 rpm for 4 min. The tablets are subjected to combined effects of abrasion and shock. The tablets are dropped at a distance of six inches on each revolution.